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Description

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Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase

In patients with chronic obstructive pulmonary disease (COPD), pro-inflammatory and pro-destructive pathways are activated, at times independent of smoke exposure, and other anti-inflammatory, anti-oxidant, or repair pathways are down-regulated, all resulting in lung destruction